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All research areas

Research areas

Metabolic Research

Incretin signalling, mitochondrial peptides and enzyme inhibition — three separate lines of research that ended up in the same place.

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What this area studies

This area covers compounds studied for their interaction with the pathways the body uses to sense and handle energy: incretin receptors, mitochondrial signalling and the enzymes that regulate cellular methylation.

The incretin line (GLP-1, GIP, glucagon) is the most documented in the catalogue: it includes molecules with published human clinical trials, which is rare in research peptides. The mitochondrial line is younger and largely preclinical.

We say which is which on every product page, because the difference between a phase-3 trial and a mouse study is the whole story.

Three facts

1902

The word came before the molecule

Bayliss and Starling described 'secretin' in 1902 and coined the term hormone for it. Incretin research — the line Retatrutide and Tirzepatide belong to — descends directly from that experiment.

16 kb

MOTS-c is not written in your nucleus

It is encoded in mitochondrial DNA, a circular genome of about 16,500 base pairs that you inherit only from your mother. Very few known peptides come from there.

NNMT

An enzyme that spends methyl groups

5-Amino-1MQ is studied as an inhibitor of nicotinamide N-methyltransferase, an enzyme that consumes methyl donors. The research question is what happens upstream when it slows down.

How this material is handled

Lyophilised and unopened, this material is stable dry at room temperature — it does not need a cold chain in transit. Refrigeration at 2–8 °C applies only after reconstitution. Each batch ships with its certificate of analysis.

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The literature, at its source

Human clinical trials per compound, live from PubMed. Not a selection of ours: what is published today, favourable or not.

This is a laboratory supply, not a research compound: it has no literature of its own.

It converts the numbers you enter. We are unable to provide dosing information, usage advice or personal guidance on any product.